Cancer Prevention and Control

What we do

Cancer is the second leading cause of death in Arizona. The American Cancer Society estimates that there will be over 40,000 new cancer cases in Arizona in 2023. Over the past 30 years, cancer mortality has steadily declined.

The primary reasons for this decline are increased cancer prevention and control (CPC), which includes early detection (e.g., biological markers), prevention (e.g., interventions or approaches to block/delay  cancer), screening, health care delivery, quality of life and/or survivorship related to cancer. More specifically, improved early detection via screening (e.g., breast cancer), reductions in smoking and improvements in the quality of cancer care are major reasons for this decrease, but much more research is needed to further reduce cancer mortality, with particular focus on underserved populations because reductions have not been as great in that population.

This highly collaborative translational team fosters the advancement of cancer prevention and control research with particular emphasis on underserved populations. The team includes community partnerships (health care, nonprofits, government, business, schools) and also engages students.

A presenter points to a bilingual slide about cancer prevention during a health education session.

Engagement

Team leads

Dorthy Sears

Dorothy Sears, PhD

Dorothy Sears holds the position of executive director and is a professor of nutrition at Arizona State University’s College of Health Solutions. She has conducted cardiometabolic disease and cancer research since 1995 and is an internationally recognized expert. Her scope of study spans the molecular to population health levels. Her transdisciplinary research approach incorporates dietary and behavioral intervention, systems biology, metabolomics, gut microbiome, epigenetics, gene expression profiling, and single-gene analyses in human and rodent models. Dr. Sears aims to discover and characterize innovative health-promoting behaviors, therapeutic targets and diagnostic tools. Currently, she is actively investing in the health benefits associated with nightly fasting and circadian alignment of food intake.

Team Co-Lead
Professor and Executive Director of Clinical and Community Translational Science, College of Health Solutions
[email protected]

Alexis Koskan, PhD

Alexis Koskan is an assistant professor of population health at Arizona State University's College of Health Solutions. Using a community-engaged research approach with training in public health and health communication, Dr. Koskan uses qualitative research and mixed methods to explore community needs, perceptions and preferences for intervention research. Her research has predominantly focused on the prevention and control of HPV-related cancer. She finds fulfillment in working in team science to conduct community-based research aimed at identifying intervention strategies that promote the utilization of disease prevention resources, specifically vaccines and cancer screening.

Team Co-Lead
Assistant Professor, College of Health Solutions
[email protected]

Alexis Koskan

Student Involvement

Students can get involved by attending our team meetings and learning about research and service opportunities from our members and community partners. Our team can help students identify potential projects and experiential learning opportunities based on faculty needs and student interests.

Please contact one of our leads for more information. 

College of Health Solutions Building

Where we work

850 PBC
850 N 5th St
Room 310G
Phoenix AZ 85004

Arizona Biomedical Collaborative
425 N 5th St
Room 123
Phoenix AZ 85004

Current projects

This study investigates the impact of prolonged nightly fasting and/or exercise intervention on fatigue, other patient reported outcomes, and inflammation among women with metastatic hormone positive breast cancer.

Major Goals: Explore the use of an 8-week PNF intervention, as compared to a Health Education (HED) control condition to change in cognition, sleep, fatigue, and quality of life among ethnically and racially diverse (≥50% Black, Hispanic, and/or Native American) breast cancer survivors with Cancer-Related Cognitive Impairment. Participant-facing title “The RolE of prolonged nightly faSTing to improve sleep and cOgnition in bREast cancer survivors (RESTORE)”. Now recruiting nationwide! [email protected]

We received an ABRC grant to create educational videos aimed at increasing prostate cancer screening among men of color. We worked with community partners to identify cancer survivors and caregivers to participate in a digital storytelling workshop over the course of one weekend (roughly 10-12 hours total).  We created five digital stories, each 2-3 minutes in length, of cancer survivors and caretakers (2 caretakers, 3 survivors) sharing their cancer-related journeys either being treated for cancer or taking care of others with prostate cancer.

DST prostate cancer "Secrets Kill" video

Developing a Physical Activity Program for Young Adult Cancer Survivors through Collaborative Input is a research study led by Dr. Diane Ehlers of the Mayo Clinic. This cross-sectional study assesses young adult cancer survivors' physical activity levels, cognition, fatigue, and quality of life. They complete a series of games to assess attention, memory, and thinking. Then, some participants may complete an optional interview aimed at co-creating a future physical activity program.

Excessive Alcohol Use and Cancer. Alcohol consumption has been linked to various cancers, including breast, colorectal, head and neck, and liver cancers. We are conducting research to identify populations at greatest risk for alcohol use disorder and cancer. After selecting an at-risk population, we will conduct community-engaged research to identify intervention strategies to reduce alcohol use.

This study will test feasibility and acceptability of Mates in Motion, a couple-based physical activity intervention for hematopoietic cell transplantation recipients and their caregiving spouses/partners; the program prescribes weekly step (walking) goals and trains couples in problem-solving skills to support one another in the achievement of these goals.

Completed projects

A series of three community-based workshops involving various, diverse leaders and stakeholders, including community health workers, to identify community perceptions and needs related to cancer prevention and control.

These annual workshops encourage students and faculty to share their current relevant research. We also ask community partners to present their organization’s mission, past successes and upcoming events. This is a great opportunity for community members, faculty and students to network. Attendees include individuals across ASU and other universities, nonprofits, governmental agencies (like the Arizona Department of Health Services), and community-based health organizations.

We are collaborating across the university to create a college-wide HPV vaccine event. Led by Dr. Carolyn Compton and with support from various campus leaders, this multidisciplinary project led up to health campaigns and a vaccine summit in fall 2024.

We recruited college men to create digital stories about their decision to vaccinate against HPV and conducted a pilot test using these materials within the college-aged male population to investigate their influence on intentions, social norms and attitudes regarding HPV vaccination.

Custom intervention designed for individuals with cancer disparities and elevated risk for obesity-related cancer.

Assess the feasibility and potential effectiveness of a prolonged nightly fasting intervention on cognition and cardiometabolic risk biomarkers among obese adults.

A presenter leads a health-focused session on physical activity and cancer survivorship, engaging a seated audience in a conference room with slides

2025 Cancer Education Event

The ASU College of Health Solutions Cancer Prevention and Control Translational Team reached out to the greater Phoenix community with a bilingual education program focused on healthy lifestyle changes for cancer prevention and control. The event, held at the Flinn Foundation in Downtown Phoenix on Saturday, May 17, was geared towards both established community partners and the public at large. Participants heard presentations about behaviors associated with cancer risk, nutrition, and cancer prevention from Dr. Dorothy Sears. Specifically, she described lifestyle behaviors and dietary approaches for reducing cancer and type 2 diabetes risk, including health-promoting food choices, nightly fasting, and avoiding calorie intake at night, as well as the relationship between type 2 diabetes and cancer. Dr. Nina Russin presented about physical activity and exercise for cancer survivors, including the American College of Sports Medicine’s Exercise is Medicine® initiative, the F.I.T.T. exercise prescription, the importance of daily balance exercises, and maintaining motivation for physical activity. All presentations were conducted in both English and Spanish, with translation services provided by Dr. Maricarmen Vizcaino of ASU’s College of Health Solutions and Dr. Ana Guzman of Unlimited Potential. Community partners who represent Check for a Lump, Cancer Matters, Amanda Hope Rainbow Angels, and were present at the event.