Department of Biomedical Informatics

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Computational Design of Peptide Inhibitors for Class B G Protein-Coupled Receptors

Research Topic: 
Bioinformatics
Personnel: 
Valentin Dinu
Andrew Bordner (Mayo Clinic)

The goal of this project is to develop new computational methods to design peptide inhibitors of class B GPCRs and to validate the methodology by experimentally testing designed inhibitors of the prototypical class B GPCR, the secretin receptor.